We're attempting to integrate Assetic into Drupal, and also eliminate the global drupal_add_css/js() functions. This would pave the way for smarter asset bundling & aggregation than we've ever had before, as well as let you use coffeescript, SASS, LESS, or any other format Assetic supports natively in your modules and themes. It also lends itself toward supporting partial page rendering, which will be critical for the SCOTCH initiative and ESI support.
Without help, this patch is very unlikely to make it in. The issue summary contains an itemized list of things that need help, including fun sorting algorithms, filesystem interactions, and overall DX questions. Something for everybody!
If you're interested in helping, contact Sam Boyer (sdboyer on Twitter and IRC) directly or post in the issue.