I needed something to be able to hide selected menu items on specific domains on site(s) using Domain Access module (http://drupal.org/project/domain). The idea was to have one global menu definition, and then be able to manipulate single menu items based on current domain.
As I have not found any module doing this, I have written my own simple implementation.
On admin menu item edit page it displays all domains and allows to mark a menu item to be displayed or be hidden on a specific domain(s). And then, surprise surprise, it hides items which should not be displayed.
Initial dev version is available in my sandbox, if anyone would like to check it out and express an opinion/request extra features etc - http://drupal.org/sandbox/maciej.zgadzaj/1209152