Seems like Dries's latest blog post should be linked to from here.

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chrowe's picture

How should you decouple Drupal?

"With RESTful web services in Drupal 8 core, Drupal can function as an API-first back end serving browser applications, native applications on mobile devices, in-store displays, even in-flight entertainment systems (Lufthansa is doing so in Drupal 8!), and much more. When building a new website or web application in 2016, you may ask yourself: how should I decouple Drupal? Do I build my website with Drupal's built-in templating layer or do I use a JavaScript framework? Do I need Node.js?"...

http://buytaert.net/how-should-you-decouple-drupal