advertising adserver

Is it possible to run non Drupal sites within/alongside a Barracuda install?

Use case:
I would like to setup an ad server for a couple of Drupal sites.

My current solution is to use OpenX Source and I'd like to avoid setting a specific server just for this application.

Coud I possibly create a specific folder for non Drupal sites, how would I point to it? Generally , is it possible and if yes, how would you go about it?

Aside from OpenX, ideal solution would be to have a Drupal ad server distribution, surprisingly I haven't found many Drupal ready solutions for serving ads.