Posted by rjbrown99 on June 15, 2010 at 5:55pm
Amazon Web Services is hosting a Cloud for the Enterprise event in Los Angeles on July 20th. I went to their last LA event and it had some good content. Specifically, they did a few case studies of highly scaled cloud sites such as reddit.com. If you are looking at AWS as a Drupal option it might be an interesting event for you to learn more.

Comments
For anyone interested in
For anyone interested in Drupal on AWS, I recommend seeing Barry Jaspan's Challenges of hosting Drupal on AWS session at DrupalCon San Francisco. I think it's the best presentation ever made about cloud hosting.
I thought their last event
I thought their last event was a major snooze.
Given the choice, I would go to see Jeff Gordon's Amazon presentation at the OC meeting on July 6th. - http://groups.drupal.org/node/75178
Event
The Reddit talk from the last event was the highlight for me as they presented a real case study. After listening to them, I also followed up and found a presentation they did at PyCon. It had even better content and here's the link. It's a bit different than Drupal but realistic case studies of scaling on EC2 - with approximate cost figures - is very useful.
http://us.pycon.org/2010/conference/schedule/event/148/
In terms of the other talk you linked to from Drupalcon, I agree with pretty much everything he said. Had that come out a year or so ago it would have saved me a lot of time. I seem to have gone down the exact same paths with S3FS, rsync, etc. I'd also add a big list of challenges with proper CDN integration and implementing a mixed http/https site.
One thing he did not point out that will save you a TON of time fighting the outbound e-mail battle: http://www.authsmtp.com. Trust me. Route your outbound mail via AuthSMTP and you hit the inbox of every major mail hosting company from Gmail through Hotmail. This one little fact took me a huge amount of personal challenge of rolling my own exim with DKIM+SPF and wondering why all my email still went to the spam bucket. After a huge round of phone calls and research AuthSMTP came out the winner and the price point is great.
I also implemented a mixed Eucalyptus stack locally that can 'cloudburst' to Amazon. That way I can host and spin up my own development machines using the exact same Amazon API and tools, and then migrate to Amazon only when I want to promote to production (and start paying!) Eucalyptus is really cool, and they also run Drupal on their community site. Good stuff.
http://www.eucalyptus.com
Thanks for the AuthSMTP
Thanks for the AuthSMTP recommendation. That's exactly what I've been looking for on a current project.